Introduction to Semax
Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic ACTH(4-7) analogue from Moscow State University. A Pro-Gly-Pro C-terminal extension improves stability. Researchers designed it to preserve ACTH’s neurotrophic effects while stripping corticosteroidogenic activity, leaving adrenal stimulation out of the picture.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.
Semax Neurobiological Mechanisms
BDNF Upregulation
Primary mechanism – documented increased BDNF expression in hippocampus, frontal cortex and basal ganglia in rodent models.
NGF Upregulation
Nerve growth factor also upregulated – relevant to peripheral nerve and neuronal survival research.
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Dopaminergic Modulation
Increased dopamine turnover in frontal regions; D1/D2 receptor signalling interactions studied.
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Neuroprotection
Antioxidant effects in brain tissue, reduced apoptotic markers, ischemia-reperfusion injury protection in rodent models.
Semax in Stroke Research
Multiple rodent studies document reduced infarct volume, decreased neurological deficit scores, and preserved cognitive function in post-ischemic animal models.
Semax Preclinical Research Areas
BDNF/NGF upregulationPrimary documented mechanism
Cerebral ischemia / stroke modelsStrongest evidence base
Cognitive and learning researchMorris maze, associative learning
NeuroinflammationMicroglial markers, cytokines
Semax Storage and Reconstitution
1
Store at -20 degrees C
Stable in lyophilized form.
2
Reconstitute with BAC water
Inject against vial wall. Swirl gently.
3
Store at 2-8 degrees C
Use within 28 days.
FenaLife supplies Semax 10mg.
Conclusion
Semax’s BDNF/NGF activity and documented neuroprotection in ischemia models give it a stronger evidence base than most nootropic research peptides. Explore FenaLife’s cognitive research catalog.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.
Source Semax 10mg at FenaLife
Research-grade, HPLC-verified purity. Fast shipping.