Introduction to Oxytocin
Oxytocin (OXT) is a nonapeptide synthesized in the hypothalamus. Its research profile has grown well beyond childbirth and lactation to cover social behaviour, stress response, metabolic regulation, and cardiovascular biology. Oxytocin acetate is the standard research-grade formulation.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.
Oxytocin Receptor Expression Sites
Brain (Amygdala, Hippocampus)
Social behaviour, fear response, reward. Primary focus of social neuroscience research.
Hypothalamus
Appetite regulation, HPA axis modulation. Metabolic and stress research.
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Heart and Vasculature
Cardioprotective effects, blood pressure regulation. Emerging cardiovascular research area.
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Pancreas and GI Tract
Insulin secretion modulation, appetite effects. Metabolic applications.
Oxytocin Social Neuroscience Research Evidence
Pair bonding prairie vole modelsFoundational animal model
Trust and cooperation human studiesKosfeld et al. Nature 2005
Social memory researchHippocampal OXTR-mediated
Fear extinction and anxietyAmygdala OXTR modulation
Autism spectrum modelsSocial cognition research
⚠️ Disulfide Bond – Critical for Activity
The Cys1-Cys6 disulfide bond is essential for oxytocin receptor binding conformation. Avoid reducing conditions (DTT, beta-mercaptoethanol) – these break the disulfide bond and inactivate the peptide.
Oxytocin Acetate Handling
1
Store lyophilized at -20 degrees C
Store away from reducing agents – disulfide bond is essential for activity.
2
Reconstitute in sterile water or saline
Readily water-soluble. Dilute to working concentration.
3
Maintain neutral pH
Oxytocin most stable near neutral pH.
FenaLife supplies Oxytocin Acetate 5mg.
Conclusion
Oxytocin acetate gives researchers access to a well-characterized GPCR system spanning social neuroscience, metabolic regulation, and cardiovascular biology.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.