Introduction to PT-141
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide derived from Melanotan II. It agonizes melanocortin receptors, primarily MC3R and MC4R, with effects mediated centrally through hypothalamic receptors. That central mechanism distinguishes it from peripherally-acting compounds.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.
PT-141 CNS Research Relevance
MC4R Hypothalamic Research
MC4R is one of the most studied hypothalamic GPCRs – regulating energy homeostasis, autonomic function, and complex behaviours.
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Appetite and Energy Research
MC3R and MC4R are critical nodes in the melanocortin energy balance system – complements leptin, GLP-1, and ghrelin research.
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Autonomic Nervous System
MC4R in brainstem and spinal cord modulates blood pressure and heart rate – relevant to cardiovascular-CNS research.
Central vs Peripheral Dissection
PT-141 central mechanism allows study of CNS-mediated outcomes separate from peripheral vascular effects.
PT-141 Research Application Evidence
MC4R signalling researchPrimary application – well characterized
Hypothalamic appetite circuitsMC3R/MC4R energy balance
Autonomic nervous systemBlood pressure, heart rate modulation
Anti-inflammatory MC1RSupporting evidence
PT-141 Storage and Reconstitution
1
Store lyophilized at -20 degrees C
Stable in sealed vial. Protect from light.
2
Reconstitute with BAC water
Add slowly against vial wall. Swirl gently.
3
Store at 2-8 degrees C
Use within 28 days.
FenaLife supplies PT-141 10mg.
Conclusion
PT-141’s central MC4R action makes it the right tool for researchers studying hypothalamic melanocortin signalling and autonomic biology. Browse FenaLife’s full peptide catalog.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.