Introduction to TB-500
TB-500 corresponds to the active actin-binding domain of thymosin beta-4 (Tβ4), an intracellular protein central to actin polymerization. Research indicates this fragment retains much of the full protein’s biological activity.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.
TB-500 Key Research Mechanisms
Actin Sequestration
Binds G-actin and modulates cytoskeletal dynamics — regulates cell migration, critical to tissue repair.
Pro-Angiogenesis
Studies documented upregulation of VEGF and endothelial cell migration in wound healing and ischemia models.
Anti-Inflammatory
Documented reduction of IL-1β and TNF-α; NF-κB signalling modulation across multiple model systems.
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Cardiac Progenitor Activation
Nature (2004): Tβ4 activates dormant epicardial progenitor cells — a significant cardiac repair research finding.
TB-500 Research Evidence by Area
Wound healing / skin repairMost extensive literature
Cardiac progenitor / ischemiaHigh-impact research area
Musculoskeletal tendon/muscleActive preclinical area
Anti-inflammatory modelsWell documented
Neurological modelsEmerging research area
TB-500 Storage and Reconstitution
1
Store lyophilized at −20°C
Protect from light and moisture.
2
Reconstitute with BAC water
Inject slowly down the vial wall. Swirl gently — do not shake.
3
Store reconstituted at 2–8°C
Use within 28 days. Minimize freeze-thaw cycles.
FenaLife supplies research-grade TB-500 10mg.
Conclusion
TB-500 has a strong preclinical base and a mechanistically distinct profile among tissue repair research compounds. Browse FenaLife’s recovery and repair catalog.
⚠️ Research Use Only
All products sold by FenaLife are intended strictly for laboratory and academic research purposes. Not for human consumption, injection, or ingestion. These statements have not been evaluated by the FDA.
Source TB-500 10mg at FenaLife
Research-grade, HPLC-verified purity. Fast shipping.